Today, oral contraception is considered the most effective way to protect against unwanted pregnancies. Nevertheless, she has many ...

Contraceptive pills "Jess": analogues, comparison, instructions and reviews

From Masterweb

In the article we will consider instructions for use and analogues for the drug "Jess".

Today, oral contraception is considered the most effective way to protect against unwanted pregnancies. Nevertheless, at the same time, she has numerous disadvantages, because of which many women are in no hurry to give them preference. The modern contraceptive "Jess" combines ease of use and the minimum list of adverse reactions. The contraceptive drug "Jess" is a new generation oral monophasic contraceptive.

The mechanism of action of these contraceptive pills is similar to that of other oral contraceptives, however, the formula of this medication has been somewhat improved and improved. This is due to the presence in their composition of drospirenone, which is a fourth generation progestogen, the effect of which on a woman's body is as close as possible to natural progesterone. Drospirenone is able to block water and sodium retention in the body caused by estrogens. Against this background, as a result of taking other oral contraceptives in women, there are negative side effects in the form of increased body weight and swelling, which leads to a very good tolerance of this drug.

In addition, drospirenone has a positive effect on the work of hormones in the premenstrual period, facilitating the condition of a woman in the case of severe forms of PMS (reduces the intensity and frequency of psychoemotional disorders, headaches, engorgement and inflammation of the mammary glands).

It is quite possible to find Jess analogues in composition and cheaper. Oral contraceptive pills "Jess" contain in their composition the minimum, in comparison with other means of similar action, the amount of estrogen - 20 mg, and this indicates the safety of this drug. Microdosing of hormones has a sparing effect on the female body, reducing the development of all kinds of complications and side reactions. The main indications for the use of this pharmaceutical are contraception, as well as the treatment of acne and severe forms of premenstrual syndrome. Analogs "Jess" are also assigned for these purposes.

Positive properties of the drug "Jess"

Women who regularly take medication observe the stabilization of the menstrual cycle, which becomes more regular, and the menstruation itself is more painful, the intensity of bleeding decreases, which prevents the occurrence of iron deficiency anemia. In addition, regular use of this medication reduces the risk of developing inflammatory pathologies in the female genital area. Also, the medication significantly reduces the discomfort that occurs before the onset of menstruation and in the middle of the cycle.

It should be noted that, according to epidemiological studies, combined oral contraceptives, including all analogues of Jess tablets, reduce the likelihood of developing endometrial, ovarian and other cancers of the female organs.

In addition, due to its high antiandrogenic activity, the drug provides a therapeutic effect for certain skin diseases (acne), normalizes the condition of nails, and reduces the oiliness of hair and skin. Many women with the use of the drug "Jess" observe breast augmentation. Also, this contraceptive helps to slow down the development of osteoporosis and is an effective preventive measure against ectopic pregnancy. But the main thing is that this medication gives a persistent contraceptive effect, in which pregnancy can occur only when the norms for taking the drug are violated or when you refuse to take it. It should be noted that this remedy for unwanted pregnancy does not protect against genital infections and STDs, therefore, if there are doubts about the sexual partner, you must additionally use barrier-type contraception.

Contraceptive counterparts "Jess" should be selected by a doctor.

Usage mode

Each pack of contraceptive pills contains 28 pills, 24 of which have a contraceptive effect, and the remaining 4 have a placebo effect, that is, they do not have medicinal properties and are used as a means, the therapeutic effect of which is based on the woman's belief in the efficacy of the medicine. This provides an opportunity to maximize the effectiveness of the drug and prevent missed tablets or start using a new package. The tablets should be taken daily, at the same time, and there is no need to take breaks between packages. Menstruation usually begins on the second or third day of taking the placebo pill and can last even after starting a new pack of medication.

Start of reception

If in the previous month the woman did not take any oral hormonal contraceptives, then taking this drug should be started on the first day of the onset of menstrual bleeding. However, it is also allowed to take pills from the second to the fifth day of the cycle, only in this case you need to use some additional methods of contraception (for example, barrier) during the first seven days of using the medication.

When switching to this drug from other oral combined contraceptives, Jess should be taken the next day after the last active pill from the package of the previous medication, no later than the next day after the usual seven-day break (if there are 21 tablets in the pack), or after use the last inactive tablet (in cases where 28 tablets per pack are active).

When switching from a contraceptive patch or vaginal ring, it is recommended to start taking this drug on the day of such contraceptives, no later than the time when a new ring is to be inserted or a new patch is applied. It is allowed to switch from a mini-drink to the use of the drug "Jess" on any day without interruption, and from a hormonal implant or means of intrauterine contraception with gestagen - on the day of removal. From contraceptive injections, the transition to the drug is carried out on the day of the next injection. In all cases, barrier contraception (condoms) should be used during the first week of taking these pills.

After an abortion, you can start drinking the Jess contraceptive immediately, and no additional contraception is required. If this medication causes severe abnormalities in the activity of the stomach (vomiting), you should proceed in the same way as in case of missing a pill, plus additional means of protection should be applied during sexual intercourse.

If it is necessary to change the timing of the onset of menstruation, you need to continue taking the tablets from the next package, while skipping the placebo from the current package of the drug. In this case, the cycle can be extended for the desired period until the active tablets from the second pack run out. Against this background, a woman may experience breakthrough uterine bleeding or spotting. Regular use of oral contraceptives "Jess" resumes after taking placebo pills.

Adverse reactions

When using this medication, the following side symptoms may occur:

• headache, migraine;
• dyspepsia;
• soreness of the mammary glands;
• irregular uterine bleeding;
• venous and arterial thromboembolism;
• psycho-emotional disorders;
• mood swings;
• change in sex drive.

As a rule, such negative manifestations can be observed only during the first months of taking the medication, during the period of adaptation of the body to the active substance. If the symptoms persist, it is necessary to consult with a specialist who can prescribe other contraceptive drugs or cancel them due to their intolerance.

Contraceptive analogues "Jess" give the same side effects.

Contraindications

The list of the main contraindications to the use of "Jess" includes:

• hypersensitivity to components;
• lactation period;
• benign or malignant tumors in the liver;
• pregnancy or suspicion of it;
• thromboembolism and thrombosis, as well as their previous conditions, including a history;
• migraine with neuralgia symptoms;
• diabetes mellitus, which is accompanied by vascular disorders;
• cerebrovascular pathology;
• hormone-dependent malignant tumors or suspicion of them;
• severe and acute forms of renal failure;
• pancreatitis with hypertriglyceridemia;
• adrenal insufficiency;
• liver failure and other liver pathologies in severe forms;
• vaginal bleeding of unknown origin.

If the fact of pregnancy is detected, the medication is immediately canceled, however, if it was inadvertently used in the early stages of pregnancy, do not worry, this does not carry an increased risk of developing defects in the fetus. It should also be noted that if one of the side effects is observed for the first time while using the drug, it must be discarded. Contraceptives "Jess" can be taken for a long time, and there is no age limit.

Analogs "Jess"

Analogs of this oral contraceptive include the following drugs:

• Delsia Dimia;
• "Lei";
• "Simicia Yamera";
• Anabella Vidora;
• Yarina;
• Janine.

The last two oral contraceptives are considered the most popular analogues of the drug "Jess", widely prescribed by specialists.

"Jess" or "Dimia"? Comparison

Both agents do a good job with their direct task - they block ovulation, suppress sex hormones, treat gynecological disorders and acne. For therapeutic purposes, oral antiandrogenic contraceptives are prescribed to treat alopecia and virilization. "Jess" and the analogue "Dimia" are generics, but they have some differences. First, they are cost and manufacturer. "Jess" can be purchased for about 1,500 rubles, and "Dimia" - for 800 rubles.

That is, "Dimia" is an analogue of "Jes", but cheaper. The price differs by 2 times, which in some cases plays a significant role in the preference of the drug. Dimia has a wider list of side effects, which include swelling, headaches, contact lens intolerance, cellulite, and weight gain. Therefore, in this case, one should carefully consider the selection of the drug and weigh the benefits and harms of possible negative reactions, take into account the large difference in price.

Let's consider another analogue of "Jes".

"Jess" or "Yarina"?

The high efficiency of the analogue of the drug "Jess" "Yarina" in the treatment of acne is associated with a rather high content of ethinyl estradiol in this drug, which provides a more noticeable and quick result. The price of these drugs is almost the same, and the treatment of acne and acne is very effective in both cases. Therefore, it is impossible to say for sure which of these funds is better, since contraindications, and adverse reactions, and the positive effect of their use are equivalent.

What other analogues in the composition of "Jess" are there?

"Jess" or "Janine"?

Both medications affect ovulatory functions (inhibit ovulation) and, in addition, make the cervical mucus thicker, which is the main obstacle to the penetration of sperm into the uterus.

The therapeutic effect is provided by the gestagenic component of both drugs. During the intake of these tablets, there is no fluid retention in the body, the body weight remains normal. A beneficial effect on lipid metabolism is also recorded. Reviews of the analogue "Jess" confirm this.

When taking hormonal tablets "Janine" it is possible to get rid of alopecia and hirsutism associated with an excess of testosterone. In addition, the contraceptive normalizes MC, relieves painful symptoms during menstruation. The drug is often prescribed for uterine fibroids and endometriosis.

The difference in price between drugs is insignificant, "Janine" is approximately 500 rubles cheaper than "Jess". Otherwise, both tools are very effective and there are no significant differences between them.

Let's consider what people think about these analogs of "Jess" in composition.

Latin name:YAZ
ATX code: G03A A12
Active substance: Drospirenone,
Ethinylestradiol
Manufacturer:BAYER WEIMAR (FRG)
Pharmacy dispensing condition: On prescription
Storage conditions: t ° up to 30 ° С, dry and dark place
Shelf life:in a blister - 5 l,
in a flex-cartridge - 3 g

The hormonal drug Jess is a combined oral contraceptive.

Composition of the preparation

For the course "24 + 4" in the Jess preparation, a set of two types of tablets is provided: active and with a placebo effect.

• Active ingredients: ethinyl estradiol (in the form of betadex clathrate) - 20 μg, drospirenone - 3 mg
• Additional ingredients that form the core and shell: lactose in the form of monohydrate, corn starch, E572, hypromellose, talc, E171, E172.

White tablets (placebo):

• Core composition: lactose in the form of monohydrate, CMK, E572
• Sheath: hypromellose, talc, E171.

Jess for a "flexible" treatment regimen is represented only by active pills. The content of the substances is identical.

• Jess Plus

Substances of structure and coating: composition of Jess Plus, hyprolose and primelose, pink varnish, hypromellose, macrogol, E171, dye.

The main substance of placebo tablets is calcium levomefolate.

Auxiliary ingredients (core and coating) - lactose, CMB, primelose, E171, colored varnish, macrogol, talc, E171, etc.

Healing properties

Jess is a combined OC that has antimineralocorticoid and antiandrogenic effects. The main components of the contraceptive trigger many different reactions, the result of which is the suppression of the possibility of ovulation and a change in the structure of the cervical secretion, making it impossible for sperm to enter the uterine cavity.

In addition, Jess hormonal pills normalize the menstrual cycle, prevent excess weight and the appearance of edema, therefore, as a rule, they are well tolerated by the body.

Ethinylestradiol is the main component providing the required action. The substance belongs to estrogen: it suppresses ovulation and changes the quality of the cervical secretion. Since the use of only one substance causes negative effects, it is supplemented with another component.

Drospirenone contained in OK eliminates the manifestations of PMS. Therefore, the drug is prescribed for women with severe undesirable symptoms: psycho-emotional disorders, discomfort and soreness in the chest, acne, increased greasiness of the skin and hair. The synthetic hormone does not possess androgenic, estrogenic, antiglucocorticoid properties; its qualities are very close to natural progesterone.

The difference between Jess and Jess Plus

Manufacturers also release another version of OK - fortified Jess Plus. It differs from the first agent by the inclusion of a third component - calcium levofoliate. Moreover, the substance is available in both types of tablets - in active and pacifiers.

The component is a derivative of folic acid, but, unlike it, it has bioactive properties, therefore it is absorbed more fully and acts faster.

Average price: 1072 rubles for a calendar package, flex-cartridge (30 pcs.) - 1713 rubles, a device with a dispenser (30 pcs.) - 2288 rubles.

Lemofolate is necessary to replenish the increased consumption and ensure the required level of folate in the female body during pregnancy and lactation. Its inclusion in the contraceptive eliminates the threat of developing an anomaly of the neural tube in the fetus in case of conception against the background of OK or immediately after the end of the course. Therefore, women planning motherhood in the near future are often told by gynecologists that it is better to switch from Jess to Jess plus.

Release forms

The contraceptive Jess is produced in the form of a set consisting of 24 active pills and 4 white pills with placebo effect.

The active tablets are enclosed in a pale pink film coating. The pills are round, convex on both sides. A regular hexagon with the DS abbreviation in the center is extruded on one of the surfaces. On the broken tablet, white contents and a pale pink shell are visible. The inactive tablets are identical in shape but differ from the active pills in their white coating. The surface also has a regular hexagon, but the inscription in the center is different - DP.

There are several types of packaging for Jess medicine:

• Tablets "24 + 4" are packed in blisters with a calendar index, enclosed in a carton box.
• The contraceptive, consisting only of active pills, is packaged in 30 pieces in special flex cartridges with or without a Clyk dispenser. The device with pills is packed together with an annotation-guide for use in cardboard boxes.

Jess Plus

Average cost: (28 pieces) - 1080 rubles, (84 pieces) - 2800 rubles.

The drug consists of a set of active and inactive tablets.

• Active (24 pcs.) - round, convex on both sides, enclosed in a pink covering. The fracture shows white contents and a pink shell. One side is marked with an embossed Z letter enclosed in a branded hexagon.
• Inactive (4 pcs.) - have an identical shape, but differ in the color of the shell - it is pale orange. The surface is marked with the letter M in a regular hexagon.

The product is packaged in blisters of 28 pieces. A pack of cardboard is completed with one plate, an admission instruction, an admission accounting calendar and a set of stickers for this, or a folding book with a set of self-adhesive stickers for keeping records of admission.

Mode of application

The peculiarities of the use of tablets are determined by the doctor, in accordance with the indications and the state of the patient's body. It is possible to carry out Jess reception according to one of the schemes: "24 + 4" and "flexible". A woman can choose the most convenient one for herself.

Method "24 + 4"

With this scheme, the tablets should be taken in accordance with the calendar on the blister. To achieve the maximum effect, they must be drunk at one hour every day, without interruptions in the course. After the end of 24 active pills, they start taking inactive pills (placebo), during which bleeding occurs like menstruation. After the end of the blister, they immediately start receiving a new one. Subject to all the rules of admission and avoidance of gaps, the cycle normalizes and bleeding occurs on one day of each month.

Flexible admission scheme

This method of contraception is used only with active pills contained in cartridges (with or without dispenser).

The pills are also taken every day, one piece together with a little water. The course is conducted without interruptions, not less than 24 days. If a break is required, it is allowed to temporarily suspend taking the pills after the 25th day of the course and no later than the 120th. The duration of such a respite is 4 days. It is inappropriate to make it longer, since the contraceptive effect decreases.

Each renewal of the course after a 4-day interval is considered a new cycle with a minimum duration of 24 days and a maximum duration of 120. Withdrawal bleeding occurs during the 4-day break.

If, during a continuous course of a hormonal drug, a woman develops spotting (or bleeding) that lasts for 3 days, then it is advisable to take a break to reduce the bleeding period.

Taking the pills is well facilitated by the device of the flick cartridge with the dispenser, since they have a function for storing the time of reception, which is displayed on the display of the device. Thus, the patient can always specify the time of appointment and detect the missing OK.

Features of receiving OK Jess

• If the woman has not previously taken any OK

Drink the first active pill on the day of the beginning of the MC, then there is no need for auxiliary means of protection. You can drink a pill for a maximum of 2-5 days, but in this case, you will need to resort to additional means of protection.

• If previously used other combined OK

It is advisable to drink Jess on the next day after the end of the previous course or strictly after the end of the prescribed break (or after the end of the placebo). If before Jess the patient used a vaginal contraceptive ring or patch, then OK is taken on the day the VC is removed or the patch is removed.

• Switching from gestagenic contraceptives

After canceling the "mini-drank" you can drink the pill on any suitable day, if there was an implant or VC - on the day of their removal. If injections were administered, the tablet is taken on the day of the next procedure. In all these cases, you should protect yourself with barrier agents for a week.

• How to drink Jess after termination of pregnancy

If the abortion was done in the first term or there was a miscarriage, then OK is taken immediately - then auxiliary measures will be required.

After interruption for the 2nd term or childbirth, the reception of Jess begins after 21-28 days (if there is no GV). If you start the course later, then from the first day of admission you will need to additionally protect yourself. But in the case of an unprotected PA that happened in this interval, it is better to postpone OK until the onset of menstruation, or make sure that there is no pregnancy with a doctor.

Jess Pill Skip

You don't have to worry about skipping inactive pills. It is better to throw away a forgotten placebo in order to exclude its intake and thereby not prolong the course of pacifiers. But if a woman could not take an active pill on time, then she should do the following:

If the delay is less than 24 hours, this will not affect the contraceptive effect. The forgotten pill should be taken as soon as possible, and the next one should be taken in accordance with the schedule.

With a delay in admission for more than a day, the contraceptive effect weakens. In this case, you must follow the rules:

• The course of admission cannot be stopped for more than 7 days (for the "24 + 4" scheme) or 4 days (for flexible use)
• In order to form a concentration of OC that can suppress the hypothalamus-pituitary-ovarian system, an uninterrupted 7-day intake of OC is required.

To avoid such situations, a warning system is provided in the cartridge with the Clyk dispenser. If Jess is missing, an exclamation mark appears on the display. He disappears after a week of admission.

In the absence of information (if the device is damaged or there is doubt about the reliability of the data), then, depending on the day of admission, you must proceed as follows:

1-7 days: drink the missed Jess pill, if the reception coincides with the next portion, take two at once. After that, it will take a week to use condoms or other non-hormonal drugs.

8-14 days of the "24 + 4" scheme and 8-24 days of the "flexible" scheme: they do the same - they drink a forgotten pill, if they coincide with the next hour of admission - two. If there have been no breaks for a week before, then you do not need to use anything additionally, if not, resort to barrier protection means.

15-24 days ("24 + 4") or 25-120 ("flexible" reception): if before that the woman did not forget to drink OK, then she just needs to make up for the omission - take a pill as soon as possible, and, if necessary, drink two pieces. If the delay happened closer to the end of the blister - take the missing pink pill from the new disc, after all 24 active ones run out - proceed to the "dummies". Additional protective equipment will be required if omissions were allowed in the previous week. Subject to the admission conditions, there is no need for enhanced protective measures. If you use a "flexible" scheme, then you should not allow forgetfulness at least for a week.

Another way of correcting the situation is allowed when a pass that occurs closer to the end of the pinkish tablets: you can not drink the forgotten remedy, but take a break - for 7 days or 4 (depending on the method of administration). And after the end of the interval, resume the reception cycle.

The concentration of OK can be reduced by vomiting or diarrhea, if less than 3-4 hours have passed after administration. To fill the shortage, you need to take another pink pill and then follow the recommendations in case of missing pills.

Withdrawal bleeding

If it is necessary to shift the time of the onset of "menstruation" with the "24 + 4" method, you must skip the placebo and, after all the pink pills have been taken, immediately start taking from a new plate.

With a delay for a shorter period, you can interrupt the intake of active tablets, the rest can be disposed of) and immediately go to a placebo (drink a maximum of 4 days). this approach allows you to shift the "monthly" by 2-3 days, and in this case they will begin against the background of the next batch of tablets.

If there is a need to postpone "menstruation" to another day, then you should reduce the amount of placebo taken by the desired number of days. Then it is by this amount that the onset of bleeding will move.

How to take Jess Plus

OK is designed for a 28-day course: first, pink pills are taken, after their end - orange pacifiers. After completing one course of Jess Plus, the instruction recommends to immediately start a new blister. The rest of the conditions for admission, replenishment of the pass - also correspond to Jess.

How to give up Jess

Abrupt cessation of hormone intake can provoke a negative reaction of the body. Therefore, in order to protect him from shock, only a physician can determine the cancellation scheme. An emergency refusal from OK is possible when it provoked life-threatening conditions. But after the condition is normalized, she must see a doctor in order to correct further actions.

During pregnancy and breastfeeding

The contraceptive medication Jess is prohibited for use by pregnant and lactating women. Despite this, conception cannot be ruled out in women with a normally functioning reproductive system. Although conception is unlikely with the correct use of the contraceptive, it can occur if the pills were missed.

In case of pregnancy, the contraceptive should be immediately canceled and consult your doctor. Despite the lack of clinical data on the negative effects of the drug on the development of the fetus, it is known that tablets have a detrimental effect on the development of offspring in animals. Therefore, such a scenario cannot be ruled out in relation to a person.

OK can affect the quality of lactation, since under the influence of tablets there is a decrease in the volume of milk released and a change in its composition. In addition, some of the active substances penetrate into breast milk and are passed on to the child, which can negatively affect his health.

Contraindications

The Jess contraceptive cannot be used if the woman has at least one of the following symptoms:

• Thrombosis (including pulmonary embolism, myocardial infarction, stroke), cerebrovascular disease at the time of the appointment of Jess or existing in the medical history
• Current or history of conditions that precede thrombosis (angina pectoris, ischemia, etc.)
• A diagnosed predisposition (congenital or acquired) to blood clots
• High threat of thrombosis of arteries and veins
• Migraine with focal neurological deficit (at the time of the appointment of Jess or presence in the medical history)
• Diabetes mellitus with concomitant vascular lesions
• Insufficient liver function and severe pathology (the possibility of using a contraceptive should be considered only after the normalization of the organ's work)
• Any neoplasms of the liver (current or history)
• Insufficiency of the kidneys and adrenal glands
• Diagnosed cancers of internal organs (including putative ones)
• Vaginal bleeding of unknown origin
• Confirmed or possible pregnancy, period of hepatitis B
• Individual hypersensitivity to Jess ingredients
• Due to the content of lactose in tablets: immunity to lactose by the body, lack of lactase, GG malabsorption.

If, at the time of the appointment of Jess, the patient had no reason to prohibit the drug, but during the course these symptoms appeared, the pills should be immediately canceled and contact the attending gynecologist.

Prescribing the contraceptive Jess should be carried out with extreme caution, with an analysis of the benefit / harm ratio for the following factors:

• Threat of thrombus formation is higher due to smoking, if the closest relatives in their youth had MI or intracranial hemorrhage, as well as due to excess weight, hypertension, frequent migraines, heart disease, serious surgery, severe injuries
• Diseases provoking circulatory disorders in the brain, diabetes, Crohn's disease, SLE, sickle cell anemia
• Hereditary angioedema
• High plasma TG
• Liver disease
• Diseases that have arisen during pregnancy or developed after previous hormone therapy
• Postpartum period.

Jess Plus birth control pills are prohibited for use in the presence of the same factors.

Precautions

When prescribing Jess, it is necessary to carefully study the existing risk factors, and during admission, carefully monitor the body's responses. In the event of adverse signs, you should consult a doctor to analyze the possibility of canceling OK.

CVS diseases

Medical research data indicate the relationship between OC and the development of thromboembolic conditions. The threat of VTE development is most pronounced in the first year of admission and after resuming the course after a break of more than one month. In the latter case, the first three months of admission are especially risky. When taking OK, the patient should pay attention to the following signs of pathology:

Deep vein thrombosis:

• Swelling on one side of the legs or along a vein
• Soreness and disturbing discomfort in the legs, which manifests itself only when standing upright or while moving
• Local temperature rise in problem areas of the legs
• Changes in the condition of the skin on the legs (redness or other shade).

PE manifestations:

• Breathing problems (severe or dyspnea)
• Sudden cough (sometimes with blood)
• Chest pains, especially when inhaling
• Vertigo
• Increased anxiety
• Heart rhythm disorder.

When these signs appear, urgent action is needed, since arterial TE can lead to stroke, MI, and impaired vascular patency. If several symptoms appear at the same time and one of them is most pronounced, then one cannot exclude the mutual strengthening of negative tendencies. In this case, Jess must be canceled immediately.

The risk of thrombosis and PE is increased:

• With age
• In smokers (especially often in women over 35)
• Due to excess weight and especially strongly - with obesity
• In the presence of pathology in close relatives
• Due to prolonged immobility
• As a result of the undergone serious surgical intervention, any operations on the legs, extensive injuries. In these cases, it is necessary to cancel the OK until full mobility is obtained. In addition, it should be borne in mind that prolonged immobilization is also considered a long stay on the plane during the flight for more than 4 hours.
• When the composition of lipoproteins in the blood changes
• With hypertension, migraine
• Due to abnormal heart valves, atrial fibrillation.

Before prescribing Jess, a woman should be informed about the risk of such phenomena and the symptoms of thrombus formation.

Cross-drug interactions

Medicines aimed at the induction of liver enzymes, when interacting with OC, increase the clearance of sex hormones, which provokes withdrawal bleeding and a change (increase or decrease) in the contraceptive effect. In case of a decrease in the effect of the contraceptive, it is recommended to additionally protect yourself with the help of other non-hormonal agents. Additional contraceptive measures should be applied throughout the course of treatment with such drugs, as well as after its termination - for another 28 days.

Drugs that weaken the effect of Jess include: antiepilepics (Phenytoin, Primidone, Carbamazepine), barbiturates, the antibiotic Rifampicin. Caution should be exercised when combined with Oxcarbazepine, Felbamat, Griseofulvin and drugs based on St. John's wort.

The action of Jess changes when combined with inhibitors of the protease of HIV or hepatitis C, some drugs of the NNRTI group. When prescribing, it is imperative to take into account the possible consequences on the content of hormones in the body.

When taken together with CYP3A4 inhibitors, Diltizem, Verapamil, grapefruit juice, there is an increase in plasma hormones (individually or all).

Jess is able to influence the metabolic processes of other drugs: increase the plasma concentration of Ciplosporin or lower Lamotrigine.

If it is necessary to combine Jess with angiotensia inhibitors and NSAIDs, the plasma potassium content should be monitored. It is especially important to conduct research in the early stages of the course.

Side effects and overdose

During the course of Jess, undesirable effects are not excluded, manifested in the form of various disorders:

• Hematopoiesis: changes in blood composition - anemia, low platelet count
• Immune system: manifestations of allergies, hypersensitivity to the components of OC
• Metabolic processes: increased appetite or anorexia, increased potassium content, decreased sodium
• Psychoemotional state: mood lability, depression, drowsiness / insomnia, lack of orgasm
• NS: headaches, vertigo, paresthesias, tremors of the limbs
• Organs of vision: conjunctivitis, dryness of the mucous membrane of the eye, decreased vision
• CVS: tachycardia, migraines, varicose veins, hypertension, vascular damage, nosebleeds, VTE, arterial thromboembolism (ATE)
• Gastrointestinal tract: nausea, abdominal pain, bloating, bouts of vomiting, gastritis, diarrhea / constipation, feeling of heaviness, oral candidiasis, dry mucous membranes, soreness in the gallbladder or inflammation
• Skin: rash, itching, chloasma, hair loss, eczema, dermatitis, peeling of the skin, hypertrichosis, striae, contact dermatitis, UV hypersensitivity, erythema multiforme
• Locomotor system: pain in the back, limbs, muscles
• Reproductive system: breast pain, breast enlargement, FCM, amenorrhea or uterine bleeding, vaginal candidiasis, hot flashes, MC disorder, vaginal dryness, breast cyst or hyperplasia, breast tumors, atrophic endometritis, ovarian cystosis, enlargement of the uterus
• Other disorders: increased sweating, edema, general weakness, endocrine disorders, increase or decrease in body weight.

If after taking Jess and Jess plus serious side effects appeared, then it is better to stop drinking the drug and consult a specialist.

To date, there are no reports of serious consequences after taking overdoses of Jess. Preclinical studies of the drug also did not record negative manifestations. It is assumed that accidental or deliberate intake of a large number of tablets can provoke increased side effects. The development of nausea, vomiting, spotting or uterine bleeding is possible.

Due to the lack of a special antidote, undesirable effects are eliminated with the help of symptomatic therapy.

Analogs

If it becomes necessary to stop taking Jess and choose a new OK, then you need to consult your attending gynecologist.

Bayer Pharma (Germany)

Average price: (21 tab.) - 1082 rubles, (63 tab.) - 2740 rubles.

A contraceptive drug containing active ingredients similar to Jess. Differs in a stronger concentration of estranidiol - its amount is 30 μg.

The drug is available in tablets. The course of admission is designed for 28 days, of which 4 days are placebo.

The remedy is taken daily.

Pros:

• Strong action
• Does not affect weight
• Improves MC, skin and hair.

Disadvantages:

• May impair immunity.

Jess's birth control pills contain an active ingredient (the form betadex clathrate ), Jess also contains the active ingredient .

In addition, the tablets contain additional ingredients: corn starch, lactose monohydrate, magnesium stearate.

The composition of the tablet shell includes hypromellose, titanium dioxide, talc, dye.

Release form

Jess hormonal pills are film coated.

Active tablets are round, biconvex, light pink in color. On the one hand, there is an engraving “DS” in a hexagon, on the fracture of the tablet there is a white core.

Placebo tablets are round, biconvex, they are covered with a white film shell. On one side of the tablet - engraving "DP" in a hexagon. At the break there is a white core.

pharmachologic effect

The abstract testifies that the drug Jess is a monophasic oral contraceptive, which also has an antiandrogenic and antimineralocorticoid effect on the body.

The contraceptive suppresses the process ovulation , and also affects the cervical secretion, as a result of which sperm cannot penetrate through it freely.

Those women who take this medicine note that their monthly cycle is more regular, their periods become less painful, and bleeding less profuse. As a result, the risk is reduced anemia ... When using combined oral contraceptives, the likelihood of ovarian cancer and endometrium .

The active substance drospirenone has an anti-mineralocorticoid effect on the body. Under its influence, the accumulation of extra pounds in the body is prevented, as well as the appearance of edema. It has a positive effect on the condition of a woman during PMS, reducing the intensity of psychoemotional disorders, chest pain in the joints, and other unpleasant symptoms.

The antiandrogenic activity of this component is noted, which determines a positive effect on the condition of the skin. As a result, the amount of acne decreases, the level of oiliness of the skin and hair decreases. The effect of drospirenone is similar to that of a natural one in the body.

Drospirenone has no estrogenic, androgenic, glucocorticoid and antiglucocorticoid activity. When combined with ethinyl estradiol, drospirenone has a beneficial effect on the lipid profile.

Pharmacokinetics and pharmacodynamics

Drospirenone after oral administration, it is absorbed quickly and almost completely. The maximum concentration is noted 1-2 hours after administration. Its bioavailability level is 76-85%. Bioavailability does not depend on the relationship between food intake and drug. When taken in cycles, the maximum serum level of drospirenone is observed between 7 and 14 days of treatment.

After oral administration, drospirenone is extensively metabolized. Only a small part of the substance is excreted unchanged. Metabolites are excreted through the kidneys and intestines. The substance is well tolerated by patients with mild to moderate hepatic insufficiency.

Ethinylestradiol after oral administration, it is absorbed completely and quickly. After consumption once, the maximum concentration is observed after 1-2 hours. The bioavailability of the component is about 60%. Metabolized completely through aromatic hydroxylation. Metabolites are excreted from the body with bile and urine.

Indications for use

Side effects

The most common side effects of Jes are noted:

• nausea;
• irregular periods;
• bleeding from the genitals of unknown origin;
• pain in the mammary glands.

Rarely serious side effects of the drug thromboembolism (venous, arterial).

The following side effects have also sometimes been reported:

• migraine ;
• depressed mood, mood swings, decreased sex drive;
• erythema multiforme .

There are a number of side effects that occur very rarely, but at the same time they can be associated with the use of the Jess remedy:

• tumors;
• hypertension ;
• aggravation of symptoms of angioedema;
• liver dysfunction ;
• influence on insulin resistance, change in glucose tolerance;
• crohn's disease ;
• chloasma ;
• nonspecific ulcerative ;
• symptoms of hypersensitivity.

Instructions for use of Jes (Way and dosage)

If a woman chooses Jess birth control pills, the instructions for use should be strictly followed by her. It is envisaged that the tablets must be taken strictly in the order indicated on their packaging. Every day, the drug should be taken at approximately the same time, washed down with an abundant amount of liquid. Instructions for the use of Jesse provide for taking one tablet per day for 28 days. The new pack should start the day after the women have taken the last pill from the previous pack. Typically, bleeding can begin 2-3 days after the withdrawal has occurred.

If a woman has not taken any hormonal contraception in the previous month, Jess begins on the first day of the monthly cycle. It is possible to start taking it on the 2-5th day of the cycle, but it is advisable to use additional barrier contraception during the first seven days of taking Jess tablets.

How to take pills when switching to them after other methods of contraception, you should ask the gynecologist who recommended this drug.

After an abortion in the early stages, you can start taking Jess immediately, without the need for additional contraceptive measures.

If childbirth or abortion occurred in the second trimester, then it is advisable to start taking Jess OK on the 21-28th day after that.

In the event that a woman missed a pill that is inactive, this can be ignored. Still, you should not take the missed inactive pills, for which they are thrown away.

If a pill is skipped, which is active, and the delay does not exceed 12 hours, in this case the protection is not reduced. You need to take the drug as soon as possible. If the delay exceeds 12 hours, the woman missed 2 tablets, or the break was even longer, in which case the level of protection is reduced. Accordingly, the longer the break, the greater the likelihood of fertilization.

Thus, the consequences of stopping taking Jess are as follows: if it is 4 days or more, the likelihood of pregnancy increases significantly. In order for an adequate suppression of the hypothalamic-pituitary-ovarian system to occur, it is necessary to take the pills continuously for seven days.

Therefore, if a woman passes, she needs to take the next pill as soon as possible, it is allowed to take two pills at once. Further, the intake of active pills continues at the usual time. The inactive ones should be thrown away and a new packaging started. In this case, bleeding is unlikely when taken, however, a slight discharge may be noted when taken.

If during the period of taking there was a break in the use of active pills, and there was no bleeding on the days of taking inactive pills, pregnancy should be excluded.

In case of development of serious gastrointestinal disorders, incomplete absorption of active substances is possible. On such days, it is necessary to use additional contraception. If a woman vomits within 4 hours after taking the pill, proceed as if skipping a pill.

How to stop taking pills and at the same time switch to other methods of contraception, it is advisable to ask a gynecologist in detail.

Overdose

There is no information on serious cases of drug overdose. As a result of an overdose, a woman may experience vomiting, nausea, the appearance of spotting, as well as metrorrhagia. Symptomatic therapy is being carried out.

Interaction

With the simultaneous use of Jess and other drugs (a number of antibiotics, enzyme inducers), it can provoke the manifestation of breakthrough bleeding, as well as a decrease in the level of reliability.

With the simultaneous use of drugs with Jess, inducing microsomal liver enzymes (this barbiturates , primidon , carbamazepine , phenytoin , rifampicin and others), the clearance of sex hormones increases.

Under the influence of some, a decrease in the intestinal-hepatic circulation of estrogens and, accordingly, a decrease in the concentration of ethinyl estradiol is possible.

During the period of simultaneous administration of drugs that affect microsomal enzymes, as well as within 28 days after the withdrawal of such drugs, additional contraception is needed. Additional contraception is needed within 7 days after taking ampicillins and tetracyclines.

Jess can affect the metabolism of other medicines.

To determine the likelihood of interaction with other drugs with Jess, you must carefully read the instructions for them.

Terms of sale

Sold by prescription in pharmacies.

Storage conditions

Jess should be stored at temperatures up to 30 ° C, protected from moisture and children.

Shelf life

Can be stored for 5 years.

special instructions

In the presence of certain risk factors, before taking Jess, you need to weigh the appropriateness of using this particular contraceptive.

It should be noted that in the process of research, a connection was found between protection with the help of oral contraceptives and an increase in the incidence of thromboembolism, venous and arterial thrombosis. However, these diseases are very rare. A higher risk of thrombosis is observed in smokers, at an older age, with obesity, migraine, heart valve disease, dyslipoproteinemia, atrial fibrillation.

With an increase in the intensity and frequency of migraines, you need to stop taking Jess.

There is also a risk of manifestation cervical cancer in women with persistent papillomavirus infection .

Rarely, women who took oral contraceptives have developed benign liver tumors. In very rare cases, malignant liver tumors have been reported.

Women at high risk of developing hyperkalemia , should determine the level of potassium in the blood during the first cycle of using the medicine Jess.

Women with hypertriglyceridemia should take into account that when taking Jess, they have an increased risk of developing pancreatitis.

If during the period of taking the drug, a woman has a marked increase in pressure, the contraceptive should be discontinued. If, through antihypertensive treatment, blood pressure indicators can be normalized, then taking the pills can be continued further.

In acute or chronic liver disorders, it is necessary to cancel the remedy until the condition returns to normal.

In the process of taking combined oral agents, some laboratory parameters may change, but they do not go beyond the normal range.

Jess, like other combined oral contraceptives, cannot protect against sexually transmitted diseases, as well as against HIV infection.

Using Jess pills for protection, the woman notes that there is no period when taking. Sometimes, more often in the first months, a woman notes that the menstrual cycle becomes irregular. As a rule, the adaptation period lasts for three cycles.

Taking the drug does not affect the ability to concentrate.

Jess's analogs

Matching ATX level 4:

Analogs of the drug Jess are contraceptives, Yarina ... There are also other counterparts from different manufacturers that are oral contraceptives. How to take similar drugs, and which one should be preferred, should be asked from the gynecologist.

The difference between Jess and Jess plus is that Jess Plus contains calcium levomefolate or folate ... Folate belongs to the B vitamins. In the body, they are not synthesized, so sometimes when choosing - Jess or Jess plus - a woman prefers the latter. What else is the difference between Jess plus and Jess, and which of the tablets to prefer, you should ask the gynecologist.

Dimia or Jess - which is better?

Dimia is an oral contraceptive that contains similar components. He is the cheaper counterpart of Jes. But the final decision on the choice of the drug must be made by the doctor.

Which is better: Claira or Jess?

Is a low-dose oral contraceptive that contains an active ingredient estradiol valerate ... This drug is indicated for women who have high levels of estrogen in the body. As a rule, Klayra is recommended for women of more mature age.

Which is better: Yarina or Jess?

Is a low-dose monophasic contraceptive that has anti-MCS and anti-androgenic effects. Yarina has a positive effect on the condition of the skin, hair, does not cause weight gain. The components in both drugs are the same, only the dose of ethinyl estradiol differs.

Which is better: Jess or Jeannine?

Jannine is a combined estrogen-gestagenic contraceptive, which contains ethinyl estradiol and. When taking Jeannine, women are more likely to notice some side effects, although the drug is an equally reliable contraceptive.

Logest or Jess - which is better?

The contraceptive contains ethinyl estradiol and. Side effects and effects on the body are similar to those of Jess. However, only a doctor can choose the optimal oral contraceptive.

Jess or Diana 35 - which is better?

The drug Diane 35 has gestagenic properties, it contains ethinyl estradiol and the antiandrogen cyproterone acetate. When taking Diana 35, women are more likely to notice a slight weight gain and some other side effects.

For children

Teenage girls can use Jess after their first period.

Sometimes adolescents are prescribed this drug for acne. Reviews of Jess for acne testify to the effectiveness of this drug.

With alcohol

Jess and alcohol can be combined if a woman drinks alcohol in small quantities and infrequently. Alcohol does not reduce the effectiveness of oral contraceptives.

During pregnancy and lactation

Pregnancy and breastfeeding are contraindications for taking Jess. In the event that pregnancy is determined when taking pills, you must immediately stop taking the contraceptive. Studies have shown that if pregnancy occurs after taking Jess, there are no negative consequences for the child.

Since oral contraceptives can negatively affect the composition and quantity of breast milk, they are not recommended for women until breastfeeding stops.

During puberty, many girls suffer from skin problems: excessive oiliness, acne, acne. As a rule, these manifestations disappear as they grow older, and treatment is mainly reduced to proper nutrition and care. But many women continue to worry about skin rashes beyond the threshold of puberty, sometimes even with the onset of menopause. If no other remedies help, new generation hormonal contraceptives come to the rescue. For example, Yarina or Jess. Doctors often prescribe them to treat acne, pimples, acne, and other skin conditions. But the positive impact is observed only in certain cases.

When pills help

There are many reasons for acne: from allergic reactions to serious liver diseases. Hormonal contraceptives have a good effect on the skin only if the woman has hormonal changes. The result of such fluctuations is often increased work of the sebaceous glands, which causes acne and acne. The use of modern contraceptives reduces the production of male sex hormones (androgens) in a woman's body and stabilizes the secretion of subcutaneous fat.

The doctor will help you choose the right drug. It is best to consult with several specialists (gynecologist, endocrinologist, dermatologist) and undergo laboratory tests. If the hormonal imbalance is confirmed, the prescribed treatment can be started. In most cases, a positive effect is achieved in the fight against acne and abscesses.

Types of hormonal contraceptives

There are many hormonal oral contraceptives available. They can be conditionally divided into two groups:

• Monophasic, with the same hormone levels during administration.
• Three-phase (combined), when the combination of hormones changes during the cycle.

According to the level of impact, each group, in turn, is subdivided into:

• Microdosed (estrogen dose up to 20 mg)
• Low-dose (up to 30 mg)
• High-dose (up to 50 mg).

Yarina and Jess belong to the monophasic group. They are similar in composition, but slightly differ in the level of exposure. Jess is a micro-dose, and Yarina is a low-dose drug, the level of hormones in the latter is slightly higher.

It is rather difficult to answer what is better to take for skin problems - Jess or Yarina. It depends on many factors and the final decision is up to the doctor. Among the patients, there are both positive and negative reviews of both drugs. Therefore, let's dwell on the properties of each in more detail in order to be able to compare.

The composition and properties of the drug Jess

In addition to its main purpose - to prevent the ovulation process - Jess has other useful properties. The main active ingredients of the drug are ethinylestradiol and the active hormonal component drospirenone. Together, they normalize many processes in the female body.

• When taking Jess, the production of androgens in the body decreases and lipid metabolism improves.
• The secretion of sebum is reduced, which has a positive effect on the condition of the skin, hair and nails.
• The monthly cycle is normalized, bleeding during menstruation decreases, and PMS becomes less painful.
• The drug contributes to a significant reduction or complete disappearance of rashes on the face, has an anti-inflammatory effect, narrows the skin pores.
• With the reception of Jess, you can not be afraid of weight gain or the occurrence of edema, he removes excess fluid and toxins from the body.

Drospirenone present in the drug is a 4th generation progestogen. Its structure is maximally similar to progesterone, the most important hormone of the female body. There is also Jess Plus, the composition of which is additionally enriched with calcium levomefolate, a form of vitamin B9 (folic acid). The drug is easily excreted in the urine and bile. It comes in pill form and is taken orally. The medicine should be taken daily, at the same time, with water. The number of tablets in a package is calculated for a full course of 4 weeks. It is undesirable to skip a dose in order to maintain the necessary level of hormones in the body.

From many patients who took Jess or Jess Plus in order to get rid of skin rashes, you can hear positive reviews about the drug. Its advantages include the fact that the agent, due to the low concentration of hormones in its composition, rarely causes side effects.

Sometimes, at the beginning of the medication, there is an increase in the number of acne. This can last for about 2 months. This manifestation is a fairly typical reaction of the body to the components of the drug, it should just wait out. Then the rashes are reduced, and the general condition of the skin becomes much better.

If the medicine did not help, or had insufficient effect, the doctor may recommend switching to a stronger, in comparison with Jess, drug - Yarin. The main contraindication: it should not be taken by young girls or nulliparous women. The transition is done gradually, after taking the last Jess pill. Breaking off the course in the middle is strongly discouraged. This can be fraught with increased side effects (if present) and a deterioration in the general condition of the body.

Full instructions for use are available here:

Characteristics and composition of the drug

Yarina also belongs to the new generation of hormonal contraceptives. The composition of the drug is almost identical to Jess, it contains the same active substances: ethinylestradiol and drospirenone. It is also produced in the version of Yarin Plus, enriched with folate. The only difference is that in Jesse, ethinyl estradiol is contained in a smaller amount (20 μg), and in Yarin - 30 μg. This increases the potency of the drug, but at the same time increases the risk and degree of side effects.

Contraindications to taking the drug are:

• Pregnancy
• Breastfeeding period
• Vaginal bleeding
• Individual intolerance
• Circulatory disorders
• Diseases of the liver and kidneys
• Diabetes
• Cardiac pathologies, etc.

Yarina for acne and other skin diseases is taken 1 tablet daily for 3 weeks. Then a break is taken for 7 days, and the course is repeated again.

As side effects in the treatment of Yarina, sometimes there may be:

• Headache
• Nausea
• Breast sensitivity
• Emotional instability
• Increased blood pressure
• Disorders of the digestive tract
• Allergic manifestations
• Decreased libido, etc.

Due to the diuretic property of drospirenone, a lot of fluid is excreted from the body. Therefore, when taking the medicine, vitamin complexes containing magnesium and potassium are additionally prescribed. For emotional instability - sedatives and vitamin B6. With the help of aids, side effects can be significantly reduced.

The same symptoms occasionally occur when taking Jes. If the side effect lasts longer than anticipated by the habituation period, drugs are gradually withdrawn and others are selected.

Which remedy to choose

Now, having the opportunity to compare drugs, evaluate side effects, contraindications and follow the doctor's recommendations, we choose the appropriate medicine. Often, experts advise starting treatment with Jess, as with a gentle remedy that has fewer side effects.

The good effectiveness of Yarina in the treatment of acne is associated with a fairly high presence of ethinyl estradiol in the composition. This ensures faster and more visible results.

The price of drugs is almost the same. Doctors gynecologists speak about the results of their use by their patients Yarina and Jess mostly positively. Hormone therapy is effective in treating acne and acne. The opinions of women are not so unambiguous: for some, the drug did not fit, or did not give the expected results. However, in fairness, it is worth noting that some of the ladies who left negative reviews prescribed the drug themselves, without consultation with specialists and preliminary examination. Or they stopped taking it without waiting for the necessary addiction period.

If the selection of the medicine was carried out correctly, then it is highly likely that Jess or Yarina will help get rid of the rashes and will not harm the woman's body.

Jess contraceptive pills are a monophasic combination drug.

In addition to the standard version of tablets, there is a drug Jess plus... These funds differ exclusively in composition.

Jess analogs in composition

There are several oral contraceptives that have a similar active ingredient (ethinyl estradiol + drospirenone).

It should be noted that Jess's analogues are exclusively imported, Russian analogues do not exist today.

Let's take a closer look:

All of the above drugs are cheaper counterparts to Jess's birth control pills.

These drugs are also effective, but experts strongly recommend that you seek advice from a gynecologist before replacing the contraceptive pill yourself.

Which drug is better

When choosing a contraceptive (Jess or Yarina, Jess or Dimia, etc.), you should first visit a gynecologist. The specialist prescribes contraception for each woman individually.

Jess's analogs have a similar active ingredient, respectively, they have the same effect on the body.

In this case, the advantage of analogs is a lower price.

When choosing a contraceptive, doctors advise you to pay attention to the following points:

• The age category of contraceptives.
• A number of side effects.
• Possible contraindications.